Development and Spontaneous Resolution of Suppurative Granulomatous Inflammation of Glans Penis Following Intravesical Administration of Bacillus Calmette-Guerin

نویسندگان

  • Yu-Hao Chang
  • Chi-Jung Chung
  • Tseng-tong Kuo
  • Hong-Shang Hong
چکیده

A 57-year-old male was found to have papillary transitional cell carcinoma of the urinary bladder and underwent a tranurethral resection of the tumor. He suffered from multiple asymptomatic red papules on glans penis after 9 th intravesical therapy with Bacillus Calmette-Guerin (BCG ). His left inguinal lymph node was enlarged and tender. The skin lesions were found to be due to suppurative granulomatous inflammation. Periodic acid-Schiff stain (PAS) and acid-fast stain (AFS) were negative. The lesions on glans penis and the enlarged inguinal lymph node resolved spontaneously few weeks later. The occurrence of granulomatous cutaneous lesions following BCG therapy is reported. (Dermatol Sinica 22 : 231-234, 2004)

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Granulomas of the penis: a rare complication of intravesical therapy with Bacillus Calmette-Guerin.

Immunotherapy with Bacillus Calmette-Guérin is widely used for treatment and prophylaxis of superficial urothelial cancer. Complications associated with Bacillus Calmette-Guérin treatment are common. The authors describe a case of granulomatous inflammation of the penis associated with intravesical Bacillus Calmette-Guérin therapy, presenting with multiple erythematous and painless nodules loca...

متن کامل

Cutaneous granulomatous reaction post intravesical BCG installation: a case report

Intravesical instillation of Bacillus Calmette-Guerin (BCG) hasbecome an established adjuvant treatment for superficial bladdercarcinoma. This treatment is associated with a relatively high rateof side effects which are mostly reversible spontaneously or canbe treated symptomatically. Serious systemic side effects are lessfrequent. One of rare complications is gran...

متن کامل

Symptomatic BCG balanitis occurring after induction of intravesical BCG immunotherapy. What is the optimal treatment duration and regimen?

Intravesical Bacillus Calmette Guerin (BCG) immunotherapy is the standard initial therapy for patients with high-grade urothelial bladder cancer without muscle invasion. While minor complications due to intravesical BCG immunotherapy are common, cutaneous infections of the glans penis are quite rare. Granulomatous balanitis can be devastating if not identified and treated early. A well-establis...

متن کامل

Safety and efficacy of intravesical bacillus Calmette-Guerin instillations in steroid treated and immunocompromised patients.

PURPOSE We assessed the safety and efficacy of intravesical bacillus Calmette-Guerin instillations in steroid treated and immunocompromised patients. MATERIALS AND METHODS We retrospectively reviewed the charts of 697 patients treated with bacillus Calmette-Guerin instillations at our institution from 1991 to 2004. In 24 patients (3.5%) an underlying comorbidity directly affecting the immune ...

متن کامل

Henoch Schönlein Purpura Nephritis Associated with Intravesical Bacillus Calmette-Guerin (BCG) Therapy

Henoch Schönlein purpura (HSP), also known as IgA vasculitis (IgAV), is a systemic small-vessel vasculitis that predominantly affects adolescents and is rare in adults. In many cases, the onset of HSP has been causally linked to an infectious disease. We encountered a case of HSP with severe renal involvement diagnosed by renal biopsy following bacillus Calmette-Guerin (BCG) therapy for bladder...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2008